Probiotics found to be helpful for sufferers of IBS

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galapogos
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Probiotics found to be helpful for sufferers of IBS

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Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study.

Background: The efficacy of probiotics in alleviating the symptoms of Irritable Bowel Syndrome (IBS) appears to be both strain- and dose-related.

Aim: To investigate the effect of LAB4, a multistrain probiotic preparation on symptoms of IBS. This probiotic preparation has not previously been assessed in IBS.

Methods: Fifty-two participants with IBS, as defined by the Rome II criteria, participated in this double blind, randomised, placebo-controlled study. Participants were randomised to receive either a probiotic preparation comprising of two strains of Lactobacillus acidophilus CUL60 (NCIMB 30157) and CUL21 (NCIMB 30156), Bifidobacterium lactis CUL34 (NCIMB 30172) and Bifidobacterium bifidum CUL20 (NCIMB 30153) at a total of 2.5 x 10(10) cfu per capsule or a placebo for 8 weeks. Participants reported their IBS symptoms using a questionnaire fortnightly during the intervention and at two weeks post-intervention.

Results: A significantly greater improvement in the Symptom Severity Score of IBS and in scores for Quality of Life, Days with Pain and Satisfaction with Bowel Habit was observed over the 8 week intervention period in the volunteers receiving the probiotic preparation than in the placebo group.

Conclusion: LAB4 multistrain probiotic supplement may benefit subjects with IBS.

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