oral proteolytic enzyme system on whey protein concentrate
Posted: Tue Nov 04, 2008 2:26 am
http://www.jissn.com/content/5/1/10Conclusion
Factors such as high protein intake and over-processing may contribute to a decreased absorption rate of WPC and lower than expected blood levels of individual amino acids. This may also cause digestion to take longer and be less complete than expected. The results of this study indicate that supplementing 50 g of WPC with 50 mg/g or 100 mg/g Aminogen®, a blend of food grade proteases from Aspergillus niger and Aspergillus oryzae patented for use as a digestive aid, significantly increased the absorption rate of WPC over controls. This is reflected in statistically significant (p ≤ 0.05) increases in postprandial AUC, TSAA levels, ISAA levels and N2 balance. Significant decreases in CRP levels and fluxes in AA levels (possibly contributing to a decrease in whole body protein metabolism) are also reported. Further, these results indicate the need for further research in the area of enzyme supplementation for a more complete digestion of protein and perhaps other processed foods.
Competing interests
This study was funded by Triarco Industries, Inc. (Wayne, NJ) through the contract research organization (CRO) Gateway Health Alliances, Inc. All research was conducted independently and according to protocol at the Laboratory of Nutrition and Nutritional Biochemistry, University of Yaounde I, Cameroon. None of the researchers have any financial interests concerning the outcome of this investigation and the results do not constitute an endorsement by the authors and/or their institutions concerning the ingredient tested.